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Research source / cBioPortal

How can a research project use cBioPortal data?

cBioPortal makes many cancer studies and genomic profiles available through a structured API. In a canXcer research project, a permitted cBioPortal record can provide study or cohort context with its source ID, version, citation, limitations, and rights intact.

Use the source for a defined question

A cBioPortal study may help a researcher locate a cohort, profile, or study-level genomic context. A project should first name its question and endpoint, then record why a selected source item is relevant.

The current canXcer connector is bounded to reviewed study metadata. It does not make every cBioPortal study, sample, or third-party annotation available for commercial use. Each study and upstream provider can have its own conditions.

Two routes can lead to one study

A cBioPortal record and a GDC record may trace back to the same TCGA study or overlapping samples. canXcer keeps both original IDs, versions, and retrieval dates and treats overlap as unknown until a reviewer can document the relationship.

Two successful requests are not two independent scientific confirmations. The private workspace supports a narrow source-overlap review; identifier normalization and a cross-source evidence map preserve reviewed relationships and unresolved gaps.

Credit the source

Public explanations should cite the original study and cBioPortal where appropriate. An annotation seen through cBioPortal may originate with CIViC, Cancer Hotspots, or another provider and retains that provider's own rights and interpretation limits. Naming a source credits its contribution; it does not imply partnership or endorsement.

Sources and further reading

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